Built in 1926, the Hotel Yorba is a former hotel in southwest Detroit that can be seen along I-75 near the Ambassador Bridge to Canada. The single version of the song was recorded in room 206 of the building which is now used as government subsidized housing.
The White Stripes shot much of the song's music video outside the hotel, but were denied permission to film inside; according to Jack White, the duo is "sort of banned for life" from the hotel.