Isabelle is a Belgian comic series drawn by Will and written by Franquin, Delporte and Macherot.
The comic first appeared in Spirou in 1970. Created by a top team of already-famous contributors to the magazine, the series gained a small but fanatical following. The first stories were written by Franquin (of Gaston Lagaffe fame), Delporte (editor of Spirou and writer of many comics) and Macherot (creator of Sybilline). Later, Delporte alone wrote the stories in collaboration with Will. Twelve albums were published until the series ended with Will's death in 2000.