Be prepared to have difficulty finding Mrs. Leatha's, but this place is worth getting a little lost for. It is located behind an RV dealership on busy US-98 west of Hattiesburg. The first thing you see when you get past the RVs is a building with lots of wood and smoke pouring out of the vent in the roof. This is what I want to see at a BBQ parlor. The restaurant is in a separate old building next door.