Clos Lucé is located at 500 metres from the royal Château d'Amboise, to which it is connected by an underground passageway. Built by Hugues d'Amboise in the middle of the fifteenth century, it was acquired in 1490 by Charles VIII of France for his wife, Anne de Bretagne. Later, it was used by Francis I, as well as his sister Marguerite de Navarre, who began writing her book entitled L'Heptaméron while living there.
In 1516, King Francis I of France invited Leonardo da Vinci to Amboise and provided him with the Clos Lucé, then called Château de Cloux, as a place to stay and work. Leonardo, a famous painter and inventor, arrived with three of his paintings, namely the Mona Lisa, Sainte Anne, and Saint Jean Baptiste. Leonardo lived at the Clos Lucé for the last three years of his life, and died there on 2 May 1519.
Today, the Clos Lucé is a Leonardo da Vinci museum that reflects the prestigious history of the region and includes forty models of the various machines designed by Leonardo.