Dr. Spiro J. Latsis (Greek: Σπύρος Λάτσης; born 1946 in Athens) is a Greek businessman with a fortune of US$2.6 billion . He ranked 464st on Forbes's 2012 World's Billionaires list. He is the son of the Greek shipping magnate, John Latsis, who died in 2003.
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The family's largest holding is its EFG Bank European Financial Group in Luxembourg, a banking conglomerate with two main banking holdings that operate in many jurisdictions. The Group holds over 40% of EFG Eurobank Ergasias SA listed in Greece as well as over 40% of EFG International listed in Switzerland.