On July 9, 2008, Arias's 28th birthday, she was indicted by a grand jury in Maricopa County, Arizona, for the first-degree murder of Alexander. She was arrested at her home later the same day and extradited to Arizona on September 5. Arias pleaded not guilty on September 11. During this time, she gave several different accounts about her involvement in Alexander's death. She originally told police that she had not been in Mesa on the day of the murder and had last seen Alexander in March 2008. Arias later told police that two intruders had broken into Alexander's home, murdering him and attacking her. Two years after her arrest, Arias told police that she killed Alexander in self-defense, claiming that she had been a victim of domestic violence.
The case was well publicized as the murder itself was so gruesome and Aria’s testimony was similary intense. The media scrutiny lead to a firestorm of information spreading around the case. During the trial, public figures freely expressed their opinions. "Jodi Arias has stated that she follows me on Twitter so I really hate to be saying that she is guilty but sadly, she is as guilty as it gets", Donald Trump wrote.