From michiganhighways.org:
"In the 1950s or 1960s, plans were laid to construct an M-52 expressway/freeway northerly from Adrian. The portions of M-52 completed in 1959 and 1962 from M-50 northerly to Manchester were constructed to limited-access standards with access only at crossroads and ample right-of-way to add an additional set of two lanes. A full cloverleaf interchange was graded out for a planned fully-controlled access interchange with a proposed US-12 freeway just north of the M-52 & US-12 junction. This interchange is still visible, especially the twin mounds of dirt for the US-12 overpasses. Why the planned expressway/freeway was cancelled is not yet clear."