Dr. Spiro J. Latsis (Greek: Σπύρος Λάτσης; born 1946 in Athens) is a Greek businessman with a fortune of US$2.6 billion . He ranked 464st on Forbes's 2012 World's Billionaires list. He is the son of the Greek shipping magnate, John Latsis, who died in 2003.
The family's largest holding is its EFG Bank European Financial Group in Luxembourg, a banking conglomerate with two main banking holdings that operate in many jurisdictions. The Group holds over 40% of EFG Eurobank Ergasias SA listed in Greece as well as over 40% of EFG International listed in Switzerland.